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Selected Publications

 

Article_110
November, 2020

PLoS ONE

Asthma and its relationship to mitochondrial copy number: results from the Asthma Translational Genomics Collaborative (ATGC) of the Trans-Omics for Precision Medicine (TOPMed) Program.

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Article_141
October, 2020

Nature

Inherited causes of clonal haematopoiesis in 97,691 whole genomes.

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Article_143
October, 2020

Circulation: Heart Failure

Polygenic Score for Beta-Blocker Survival Benefit in European Ancestry Patients with Reduced Ejection Fraction Heart Failure.

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Article_142
September, 2020

American Journal of Respiratory and Critical Care Medicine

Mapping the 17q12-21.1 Locus for Variants Associated with Early-onset Asthma in African Americans.

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Article_140
May, 2020

European Journal of Clinical Pharmacology

Effectiveness of beta blockers in patients with and without a history of myocardial infarction.

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Article_139
April, 2020

Genetics

Lung Function in African American Children with Asthma Is Associated with Novel Regulatory Variants of the KIT Ligand KITLG/SCF and Gene-By-Air-Pollution Interaction.

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Article_138
November, 2019

Expert Review of Precision Medicine and Drug Development

How does race and ethnicity effect the precision treatment of asthma?

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Article_137
November, 2019

Cardiovascular Drugs and Therapy

Association of Regulatory Genetic Variants for Protein Kinase Cα with Mortality and Drug Efficacy in Patients with Heart Failure.

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Article_136
September, 2019

Chest Journal

Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children with asthma.

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Article_133
September, 2019

The Pharmacogenomics Journal

A genome-wide association and admixture mapping study of bronchodilator drug response in African Americans with asthma.

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Article_135
August, 2019

Journal of Ultrasound in Medicine

The Hyperechoic Appearance of the Deltoid Muscle on Shoulder Ultrasound Imaging as a Predictor of Diabetes and Prediabetes.

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Article_134
July, 2019

Circulation: Cardiovascular Quality and Outcomes

Performance of the Meta-Analysis Global Group in Chronic Heart Failure Score in Black Patients Compared with Whites.

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Article_132
May, 2019

The Journal of Allergy and Clinical Immunology

Integrative approach identifies corticosteroid response variant in diverse populations with asthma.

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Article_131
March, 2019

The Journal of Allergy and Clinical Immunology

An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos.

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Article_127
February, 2019

Nature Communications

Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.

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Article_130
November, 2018

Nature Genetics

Assembly of a pan-genome from deep sequencing of 910 humans of African descent.

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Article_129
November, 2018

Thorax

Secondhand smoke exposure and asthma outcomes among African American and Latino children with asthma.

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Article_127
August, 2018

Nature Communications

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals.

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Article_128
August, 2018

Nature Genetics

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

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Article_126
July, 2018

Nature Communications

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

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Article_126
July, 2018

Nature Communications

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

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Article_125
July, 2018

diabetes

Genetic Variants in CPA6 and PRPF31 Are Associated With Variation in Response to Metformin in Individuals With Type 2 Diabetes

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Article_124
June, 2018

American Journal of Respiratory and Critical Care Medicine

NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Whole Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma.

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Article_123
May, 2018

Journal of the American Heart Association

Race and beta-blocker survival benefit in patients with heart failure: an investigation of self-reported race and proportion of African genetic ancestry.

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Article_122_StatMethodsMedRes
March, 2018

Statistical Methods in Medical Research

An efficient genome-wide association test for mixed binary and continuous phenotypes with applications to substance abuse research.

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Article_120_NatGen
January, 2018

Nature Genetics

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

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Article_119_JACC
November, 2017

Journal of the American College of Cardiology: Heart Failure

Targeted Metabolomic Profiling of Plasma and Survival in Heart Failure Patients.

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IJAS_54_08_COVER.indd
October, 2017

Journal of Asthma

Breastfeeding associated with higher lung function in African American youths with asthma.

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Article_116_BMCBioinformatics_2017
August, 2017

BMC Bioinformatics

Identifying pleiotropic genes in genome-wide association studies from related subjects using the linear mixed model and Fisher combination function.

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Article_115_PLoSGen_2017April
April, 2017

PLOS Genetics

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African ancestry anthropometry genetics consortium.

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Article_114_SciReports
April, 2017

Scientific Reports

Identifying tagging SNPs for African specific genetic variation from the African Diaspora Genome.

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Article_113
January, 2017

Journal of Allergy and Clinical Immunology: In Practice

Predictive properties of the Asthma Control Test and its component questions for severe asthma exacerbations.

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Article_110
January, 2017

PLOS ONE

Identifying Pleiotropic Genes in Genome-Wide Association Studies for Multivariate Phenotypes with Mixed Measurement Scales.

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Article_108
November, 2016

Clinical & Experimental Allergy

Maternal age and asthma in Latino populations.

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Article_107
October, 2016

Nature Communications

A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome.

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Article_106
October, 2016

Nature Communications

Challenges and disparities in the application of personalized genomic medicine to populations with African Ancestry.

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Article_105
September, 2016

Nature Genetics

Variation in the Glucose Transporter gene SLC2A2 is associated with glycaemic response to metformin.

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Article_104
August, 2016

PLOS ONE

Association of PAI-1 and Early Life Infections with Asthma Risk, Exacerbations, and Reduced Lung Function.

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Article_103
July, 2016

Annals of Allergy, Asthma & Immunology

Sensitization to mouse and cockroach allergens and asthma morbidity in urban minority youth: Genes-environments and Admixture in Latino American (GALA-II) and Study of African-Americans, Asthma, Genes, and Environments (SAGE-II).

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Article_102
June, 2016

American Journal of Respiratory and Critical Care Medicine

Air Pollution and Lung Function in Minority Youth with Asthma in the GALA II & SAGE II Studies.

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Article_101
June, 2016

American Journal of Preventive Medicine

Long-term Management of Low Back Pain with Opioids and NSAIDs in a Health System.

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Article_100
May, 2016

Journal of Allergy and Clinical Immunology

Assessing differences in inhaled corticosteroid response by self-reported race-ethnicity and genetic ancestry among individuals with asthma.

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Article_99b
January, 2016

BMC Bioinformatics

An efficient genome-wide association test for multivariate phenotypes based on the Fisher combination function.

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Article_98
December, 2015

Transplantation Proceedings

Race, calcineurin inhibitor exposure and renal function after solid organ transplantation.

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Article_97
December, 2015

Journal of Cardiovascular Translational Research

Genetic Factors Influencing B-type Natriuretic Peptide-Mediated Production of Cyclic Guanosine Monophosphate and Blood Pressure Effects in Heart Failure Patients.

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Article_95
December, 2015

Nature Genetics

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies 10 novel risk loci for atopic dermatitis.

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Article_96
November, 2015

PLOS ONE

Powerful tests for multi-marker association analysis using ensemble learning.

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Article_94
September, 2015

Journal of Cardiovascular Medicine

Race and association of angiotensin converting enzyme/angiotensin receptor blocker exposure with outcome in heart failure.

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YMAI_v135_i6_COVER.indd
June, 2015

Journal of Allergy and Clinical Immunology

Genome-wide Association Study and Admixture Mapping Reveal New Loci Associated with Total IgE Levels in Latinos.

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Article_91
February, 2015

The Diabetes Educator

A randomized controlled trial to provide adherence information and motivational interviewing to improve diabetes and lipid control.

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Article_89
January, 2015

Journal of Cardiac Failure

Association of Anti-Diabetic Medications Targeting the Glucagon-Like Peptide-1 Pathway and Heart Failure Events in Patients with Diabetes

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Article_88
January, 2015

Nature Communications

Ethnic-Specific Associations of Rare and Low Frequency DNA Sequence Variants with Asthma.

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Article_87
January, 2015

Journal of Allergy and Clinical Immunology

Genetic ancestry influences asthma susceptibility and lung function among Latinos.

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Article_86
October, 2014

Human Molecular Genetics

Genome-wide interaction studies reveal sex-specific asthma risk alleles.

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Article_85
September, 2014

The Journal of Clinical Endocrinology & Metabolism

Differing effects of metformin on glycemic control by race-ethnicity.

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Article_83
September, 2014

Journal of Cardiac Failure

Genetic and Non-Genetic Factors Influencing Pharmacokinetics of B-type Natriuretic Peptide.

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Article_84
August, 2014

BMC Medical Genomics

Integrated Genome-wide Association, Coexpression Network, and Expression Single Nucleotide Polymorphism Analysis Identifies Novel Pathways in Allergic Rhinitis.

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Article_82
August, 2014

American Journal of Respiratory and Critical Care Medicine

Nocturnal asthma and the importance of race-ethnicity and genetic ancestry.

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Article_81
August, 2014

The Pharmacogenomics Journal

Gene-based association identifies SPATA13-AS1 as a pharmacogenomic predictor of inhaled short-acting beta-agonist response in multiple population groups.

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Article_80
August, 2014

Journal of Allergy and Clinical Immunology

Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study.

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Article_79
May, 2014

Pain Physician

Policies and events affecting prescription opioid use for non-cancer pain among an insured patient population.

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Article_78
January, 2014

Journal of Pharmacogenomics & Pharmacoproteomics

Genomic loci evaluation with albuminuria in new-onset insulin dependent diabetic patients.

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Article_77
January, 2014

Journal of Allergy and Clinical Immunology

Genome-wide association study of lung function phenotypes in a founder population.

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Article_76
November, 2013

American Journal of Respiratory and Critical Care Medicine

Socioeconomic status and childhood asthma in urban minority youths. The GALA II and SAGE II studies.

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Article_75
November, 2013

Bioinformatics

Efficient Inference of Local Ancestry.

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Article_97
October, 2013

Journal of Cardiovascular Translational Research

Association of Genetic Variation with Gene Expression and Protein Abundance within the Natriuretic Peptide Pathway.

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Article_73
October, 2013

Journal of Allergy and Clinical Immunology

Factors associated with degree of atopy in Latino children in a nationwide pediatric sample: The Genes-environments and Admixture in Latino Asthmatics (GALA II) study.

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Article_72
September, 2013

Annals of Allergy Asthma and Immunology

Real world effects of once vs. greater daily inhaled corticosteroid dosing on medication adherence

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nature genetics - Keoki Williams, MD
June, 2013

Nature Genetics

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.

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Psychosomatic Medicine, April 2013
April, 2013

Psychosomatic Medicine

Examining the Relationship Between Depression and Asthma Exacerbations in a Prospective Follow-Up Study.

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article2
April, 2013

Journal of Allergy and Clinical Immunology

A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations

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American Journal of Cardiology
February, 2013

American Journal of Cardiology

Effect of Ezetimibe on Major Atherosclerotic Disease Events and All-Cause Mortality.

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Plos One
February, 2013

PLoS One

Genetic Ancestry-Smoking Interactions and Lung Function in African Americans: A Cohort Study.

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allergy-clinical-immunology12_12
December, 2012

Journal of Allergy and Clinical Immunology

Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans

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allergy-clinical-immunology12_12
December, 2012

Journal of Allergy and Clinical Immunology

Genetic ancestry and its association with asthma exacerbations among African American subjects with asthma

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allergy-clinical-immunology_10_12
October, 2012

Journal of Allergy and Clinical Immunology

Genetic variation in B cell–activating factor of the TNF family (BAFF) and asthma exacerbations among African American subjects

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Plos One
June, 2012

PLoS One

Genetic Ancestry-Smoking Interactions and Lung Function in African Americans: A Cohort Study

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allergy
June, 2012

Journal of Allergy and Clinical Immunology

Effect of secondhand smoke on asthma control among black and Latino children.

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allergy-clinical-immunology5_12
May, 2012

Journal of Allergy and Clinical Immunology

The relationship between combination inhaled corticosteroid and long-acting β-agonist use and severe asthma exacerbations in a diverse population

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circulation-heart-failure3_12
March, 2012

Circulation: Heart Failure

Association of β-Blocker Exposure With Outcomes in Heart Failure Differs Between African American and White Patients

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allergy-clinical-immunology12_11
December, 2011

Journal of Allergy and Clinical Immunology

Quantifying the proportion of severe asthma exacerbations attributable to inhaled corticosteroid nonadherence

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pediatrics9_11
September, 2011

Pediatrics

Ethnic Variability in Persistent Asthma After In Utero Tobacco Exposure

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nature-genetics7-11
July, 2011

Nature Genetics

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

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allergy-clinical-immunology12_10
December, 2010

Journal of Allergy and Clinical Immunology

Factors predicting inhaled corticosteroid responsiveness in African American patients with asthma

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allergy-clinical-immunology9_10
September, 2010

Journal of Allergy and Clinical Immunology

Dual-specificity phosphatase 1 as a pharmacogenetic modifier of inhaled steroid response among asthmatic patients

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circulation9_10
September, 2010

Circulation

Multicenter Cluster-Randomized Trial of a Multifactorial Intervention to Improve Antihypertensive Medication Adherence and Blood Pressure Control Among Patients at High Cardiovascular Risk (The COM99 Study)

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allergy-clinical-immunology8_10
August, 2010

Journal of Allergy and Clinical Immunology

A cluster-randomized trial to provide clinicians inhaled corticosteroid adherence information for their patients with asthma

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new-england-journal-medicine7_10
July, 2010

New England Journal of Medicine

Genetic Ancestry in Lung-Function Predictions

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Journal of Clinical Endocrinology and Metabolism
February, 2010

Journal of Clinical Endocrinology and Metabolism

Thiazolidinedione Use and the Longitudinal Risk of Fractures in Patients with Type 2 Diabetes Mellitus

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pds6_09
June, 2009

Pharmacoepidemiology and Drug Safety

Relationship between thiazolidinedione use and cardiovascular outcomes and all-cause mortality among patients with diabetes: a time-updated propensity analysis

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ajr12_08
December, 2008

American Journal of Respiratory and Critical Care Medicine

Race-Ethnic Differences in Factors Associated with Inhaled Steroid Adherence among Adults with Asthma

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Allergy-Asthma-Immunology11_08
November, 2008

Annals of Allergy Asthma and Immunology

Relationship between recent short-acting β-agonist use and subsequent asthma exacerbations

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allergy-clinical-immunology10_08
October, 2008

Journal of Allergy and Clinical Immunology

Differences in allergic sensitization by self-reported race and genetic ancestry

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Allergy-Asthma-Immunology2_08
February, 2008

Annals of Allergy Asthma and Immunology

Gene-environment interactions between CD14 C-260T and endotoxin exposure on Foxp3+ and Foxp3− CD4+ lymphocyte numbers and total serum IgE levels in early childhood

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Archives-Internal-Medicine11_07
November, 2007

Archives of Internal Medicine

Improving Asthma Care Through RecertificationA Cluster Randomized Trial

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allergy-clinical-immunology11_07
November, 2007

Journal of Allergy and Clinical Immunology

Patients with asthma who do not fill their inhaled corticosteroids: A study of primary nonadherence

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allergy-clinical-immunology1_07
January, 2007

Journal of Allergy and Clinical Immunology

Race-ethnicity, crime, and other factors associated with adherence to inhaled corticosteroids

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allergy-clinical-immunology10_06
October, 2006

Journal of Allergy and Clinical Immunology

Gene-environment interactions with CD14 C-260T and their relationship to total serum IgE levels in adults

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obesity9_06
September, 2006

Obesity (Silver Spring)

Long-Term Effects of Obesity on Employment and Work Limitations Among U.S. Adults, 1986 to 1999

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Diabetes-Care1_06
January, 2006

Diabetes Care

A Single Factor Underlies the Metabolic Syndrome A confirmatory factor analysis

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allergy-clinical-immunology7_05
July, 2005

Journal of Allergy and Clinical Immunology

Timing and intensity of early fevers and the development of allergies and asthma

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Allergy-Asthma-Immunology3_05
March, 2005

Annals of Allergy Asthma & Immunology

The role of endotoxin and its receptors in allergic disease

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allergy-clinical-immunology12_04
December, 2004

Journal of Allergy and Clinical Immunology

Relationship between adherence to inhaled corticosteroids and poor outcomes among adults with asthma

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Diabetes-Care12_04
December, 2004

Diabetes Care

Clinical Outcomes and Adherence to Medications Measured by Claims Data in Patients With Diabetes

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allergy-clinical-immunology2_04
February, 2004

Journal of Allergy and Clinical Immunology,

The relationship between early fever and allergic sensitization at age 6 to 7 years

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