Selected Publications

 

Asthma and its relationship to mitochondrial copy number: results from the Asthma Translational Genomics Collaborative (ATGC) of the Trans-Omics for Precision Medicine (TOPMed) Program.

Inherited causes of clonal haematopoiesis in 97,691 whole genomes.

Polygenic Score for Beta-Blocker Survival Benefit in European Ancestry Patients with Reduced Ejection Fraction Heart Failure.

Mapping the 17q12-21.1 Locus for Variants Associated with Early-onset Asthma in African Americans.

Lung Function in African American Children with Asthma Is Associated with Novel Regulatory Variants of the KIT Ligand KITLG/SCF and Gene-By-Air-Pollution Interaction.

How does race and ethnicity effect the precision treatment of asthma?

Association of Regulatory Genetic Variants for Protein Kinase Cα with Mortality and Drug Efficacy in Patients with Heart Failure.

Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children with asthma.

The Hyperechoic Appearance of the Deltoid Muscle on Shoulder Ultrasound Imaging as a Predictor of Diabetes and Prediabetes.

Performance of the Meta-Analysis Global Group in Chronic Heart Failure Score in Black Patients Compared with Whites.

Integrative approach identifies corticosteroid response variant in diverse populations with asthma.

An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos.

Assembly of a pan-genome from deep sequencing of 910 humans of African descent.

Secondhand smoke exposure and asthma outcomes among African American and Latino children with asthma.

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals.

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

Genetic Variants in CPA6 and PRPF31 Are Associated With Variation in Response to Metformin in Individuals With Type 2 Diabetes

NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Whole Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma.

Race and beta-blocker survival benefit in patients with heart failure: an investigation of self-reported race and proportion of African genetic ancestry.

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Targeted Metabolomic Profiling of Plasma and Survival in Heart Failure Patients.

Breastfeeding associated with higher lung function in African American youths with asthma.

Identifying pleiotropic genes in genome-wide association studies from related subjects using the linear mixed model and Fisher combination function.

Identifying tagging SNPs for African specific genetic variation from the African Diaspora Genome.

Predictive properties of the Asthma Control Test and its component questions for severe asthma exacerbations.

Identifying Pleiotropic Genes in Genome-Wide Association Studies for Multivariate Phenotypes with Mixed Measurement Scales.

Maternal age and asthma in Latino populations.

Challenges and disparities in the application of personalized genomic medicine to populations with African Ancestry.

Variation in the Glucose Transporter gene SLC2A2 is associated with glycaemic response to metformin.

Association of PAI-1 and Early Life Infections with Asthma Risk, Exacerbations, and Reduced Lung Function.

Sensitization to mouse and cockroach allergens and asthma morbidity in urban minority youth: Genes-environments and Admixture in Latino American (GALA-II) and Study of African-Americans, Asthma, Genes, and Environments (SAGE-II).

Long-term Management of Low Back Pain with Opioids and NSAIDs in a Health System.

Assessing differences in inhaled corticosteroid response by self-reported race-ethnicity and genetic ancestry among individuals with asthma.

An efficient genome-wide association test for multivariate phenotypes based on the Fisher combination function.

Race, calcineurin inhibitor exposure and renal function after solid organ transplantation.

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies 10 novel risk loci for atopic dermatitis.

Powerful tests for multi-marker association analysis using ensemble learning.

Race and association of angiotensin converting enzyme/angiotensin receptor blocker exposure with outcome in heart failure.

Genome-wide Association Study and Admixture Mapping Reveal New Loci Associated with Total IgE Levels in Latinos.

Association of Anti-Diabetic Medications Targeting the Glucagon-Like Peptide-1 Pathway and Heart Failure Events in Patients with Diabetes

Ethnic-Specific Associations of Rare and Low Frequency DNA Sequence Variants with Asthma.

Genetic ancestry influences asthma susceptibility and lung function among Latinos.

Genome-wide interaction studies reveal sex-specific asthma risk alleles.

Genetic and Non-Genetic Factors Influencing Pharmacokinetics of B-type Natriuretic Peptide.

Integrated Genome-wide Association, Coexpression Network, and Expression Single Nucleotide Polymorphism Analysis Identifies Novel Pathways in Allergic Rhinitis.

Nocturnal asthma and the importance of race-ethnicity and genetic ancestry.

Gene-based association identifies SPATA13-AS1 as a pharmacogenomic predictor of inhaled short-acting beta-agonist response in multiple population groups.

Policies and events affecting prescription opioid use for non-cancer pain among an insured patient population.

Genomic loci evaluation with albuminuria in new-onset insulin dependent diabetic patients.

Genome-wide association study of lung function phenotypes in a founder population.

Socioeconomic status and childhood asthma in urban minority youths. The GALA II and SAGE II studies.

Association of Genetic Variation with Gene Expression and Protein Abundance within the Natriuretic Peptide Pathway.

Factors associated with degree of atopy in Latino children in a nationwide pediatric sample: The Genes-environments and Admixture in Latino Asthmatics (GALA II) study.

Real world effects of once vs. greater daily inhaled corticosteroid dosing on medication adherence

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.

A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations

Effect of Ezetimibe on Major Atherosclerotic Disease Events and All-Cause Mortality.

Genetic Ancestry-Smoking Interactions and Lung Function in African Americans: A Cohort Study.

Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans

Genetic variation in B cell–activating factor of the TNF family (BAFF) and asthma exacerbations among African American subjects

Genetic Ancestry-Smoking Interactions and Lung Function in African Americans: A Cohort Study

Effect of secondhand smoke on asthma control among black and Latino children.

The relationship between combination inhaled corticosteroid and long-acting β-agonist use and severe asthma exacerbations in a diverse population

Quantifying the proportion of severe asthma exacerbations attributable to inhaled corticosteroid nonadherence

Ethnic Variability in Persistent Asthma After In Utero Tobacco Exposure

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

Factors predicting inhaled corticosteroid responsiveness in African American patients with asthma

Multicenter Cluster-Randomized Trial of a Multifactorial Intervention to Improve Antihypertensive Medication Adherence and Blood Pressure Control Among Patients at High Cardiovascular Risk (The COM99 Study)

A cluster-randomized trial to provide clinicians inhaled corticosteroid adherence information for their patients with asthma

Genetic Ancestry in Lung-Function Predictions

Relationship between recent short-acting β-agonist use and subsequent asthma exacerbations

Differences in allergic sensitization by self-reported race and genetic ancestry

Gene-environment interactions between CD14 C-260T and endotoxin exposure on Foxp3+ and Foxp3− CD4+ lymphocyte numbers and total serum IgE levels in early childhood

Patients with asthma who do not fill their inhaled corticosteroids: A study of primary nonadherence

Race-ethnicity, crime, and other factors associated with adherence to inhaled corticosteroids

Gene-environment interactions with CD14 C-260T and their relationship to total serum IgE levels in adults

Long-Term Effects of Obesity on Employment and Work Limitations Among U.S. Adults, 1986 to 1999

Timing and intensity of early fevers and the development of allergies and asthma

The role of endotoxin and its receptors in allergic disease

Relationship between adherence to inhaled corticosteroids and poor outcomes among adults with asthma

Clinical Outcomes and Adherence to Medications Measured by Claims Data in Patients With Diabetes